IMAN: Interlog protein network reconstruction, Matching and ANalysis

نویسندگان

  • Mohieddin Jafari
  • Payman Nickchi
  • Abdollah Safari
  • Soheil Jahangiri
  • Mehdi Mirzaie
چکیده

IMAN is an open-source R package that offers users to reconstruct Interlog Protein Network (IPN) integrated from several Protein-protein Interaction Networks (PPIN). Users can overlay different PPINs to mine conserved common network between diverse species. Currently STRING database is applied to extract PPINs with all experimental and computational interaction prediction methods. IMAN helps to retrieve IPN with different degrees of conservation to employ for better protein function prediction and PPIN analysis. Availability: IMAN package does not require any registration and is freely available at http://bs.ipm.ac.ir/softwares/IMAN or http://jafarilab-pasteur.com/content/software/IMAN.html. Contact: [email protected] Supplementary information: Supplementary data are available at Bioinformatics online.

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تاریخ انتشار 2016